Jul 02, 2015 the iv route was linked with higher rates of all adverse events, the sc route with moderate rates, and the oral route with fewer overall rates. There are various routes of drug administration, here in this video, we will explain you about oral routes in hindi. Routes of drug administration oral po oral administration will be covered in more detail in subsequent chapters. Sublingual and buccal medication administration are ways to take certain oral drugs. Routes of administration factors to be considered when. Oral route has a slow onset of action, hence not used in.
Bliss gvs pharma limited uncategorized advantages and disadvantages of suppositoriespessaries or rectalvaginal route of drug administration does not cause nausea and vomiting due to gastric irritation in case of oral therapy. Of course it is pointless to say that one of these dosage forms which are taken orally tablets, capsules, oral suspensions, solutions and emulsions is the best as each one. This is the most frequently used route of drug administration and is the most convenient and costeffective. What are the advantages and disadvantages of oral route drug. More specifically, in terms of the oral route of drug administration different dosage forms were analyzed, discussed and their advantages and disadvantages were compared. Advantages and disadvantages of the parenteral route. Routes of administration of a drug are determined by its physical and chemical properties, patient characteristics and the rapidity of response desired. Dosage form design may also be used modify the rate of absorption. The transdermal route apart from the abovementioned advantages and provision of long period of analgesia may be more convenient, especially for patients who are unable to take drugs orally. Appropriate for any patient, whatever the age is the most natural and easiest route of administration.
The drugs administration by this route generally affects to the part to which they are applied. Parenteral drug administration their types, advantages. What are the advantages and disadvantages of topical. Choose from 500 different sets of drug routes administration advantages disadvantages flashcards on quizlet. An early version of a dry powder inhaler dpi was the aerohalor, used to administer penicillin dust to treat respiratory infections. Learn the differences, pros, cons, and considerations for each.
Aerosols local topical route of drug administration in this route the drug is applied on the skin. An oral drug might be destroyed or diluted by acidic fluids in the stomach an oral drug might be too readily metabolized by the liver and eliminated from the body the patient is unconscious and needs medication nausea and vomiting or severe. The advantages of topical antibiotics include the following 55, 63. Advantages and disadvantages of suppositoriespessaries or.
Intravenous therapy in healthcare advantages, complications, applications and latest news when substances i. Oral route it is the most common and acceptable route for drug administration. American academy of pediatrics alternative routes of drug. That is how well your body uses the drug upon administration. Inhalation is a very old method of drug delivery, and in the 20th century it became a mainstay of respiratory care, known as aerosol therapy. That is the drug acts only at the site of application and. Pdf common routes of drug administration monica may lopez. For a more detailed description of the specific methodology involved in drug administration, the references at the end of this chapter include several excellent resources on this topic. What are the advantages and disadvantages of parenteral dosages. Click again to see term tap again to see term click card to see definition tap card to see definition the routes of administration dont deal with the gi tract. Bioavailability of drugs administered orally varies greatly. The route of administration is the way through which the dosage form is.
This route is one of the safest route as the drug cannot product poisonous effects. These changes have often resulted in improved patient adherence to. This method makes use of a drip chamber that does not allow the air to come into. The oral administration route is preferred over the various other administration routes of drug delivery due to the many advantages it exhibits. Routes of drug administration ppt pdf 10 routes of drug. Aerosols localtopical route of drug administration in this route the drug is applied on the skin. These advantages include safety, good patient compliance, ease of ingestion, pain avoidance, and versatility to accommodate various types of drugs sastry et al. Our understanding of drug transport across tissues has increased. Iv delivery permits a rapid effect and a maximal degree of control over the circulating levels of the drug.
Rapid onset of action due to rapid access to circulation. Principles and modes of drug administration springerlink. Oral drug administration an overview sciencedirect topics. The drug appears in blood within 1 minute, and peak blood levels of most medications are achieved generally within 10 to 15 minutes, which is substantially faster than when the same drugs are administered by the orogastric route.
Dosage forms are tablet, capsule, syrup, mixture, etc. A route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body routes of administration are generally classified by the location at which the substance is applied. However, there are some disadvantages of the oral route of drug administration involving the long time the drug needs in order to show an effect as well as the interaction of drug substances with enzymes andor secretions of the gastrointestinal tract. During the past 20 years, advances in drug formulations and innovative routes of administration have been made. Advantages and disadvantages of parenteral administration. Advantages are that the route is reliable and is acceptable for selfadministration.
Oral route many drugs can be administered orally as liquids, capsules, tablets, or chewable tablets. Many medications are taken orally because they are intended to have a systemic effect, reaching different parts of the body via the bloodstream, for example. As its the simplest and easiest way for any patient to take a medication. Oral po administration is the most frequently used route of administration because of its simplicity and convenience, which improve patient compliance. A drug given parenterally is one given by a route other than the mouth topical dosage forms are considered separately. The oral route of administration is the safest, most economical and the most convenient way of giving medicines. The three main parenteral routes of drug administration are iv, im, and sc, and in all cases administration is usually via a hollow needle. Condition of the patient unconscious, vomiting, diarrhoea. Routes of drug administration advantages of inhalation rapid action of the drug, with local effects with in the respiratory tract potent drugs may be given in small. Each route of administration has distinct advantages and disadvantages.
Alternative routes of drug administrationadvantages and. Dosage, design, and pharmacotherapy success chapter pdf available january 2018 with 19,343 reads how we measure reads. A list of commonly used routes of drug administration can be found below, along with useful information about dosage and abbreviations. The development of alternative methods of drug administration has improved the ability of physicians to manage specific problems. Because the oral route is the most convenient and usually the safest and least expensive, it is the one most. Winner of the standing ovation award for best powerpoint templates from presentations magazine. The mouth route is the most commonly used route of drug administration due to the ease in which the drugs can be taken.
Drug and patientrelated factors determine the selection of routes for drug administration. As compared to other dosage forms, parenteral administration offers some selective advantages. The oral route is considered as the first choice of route of drug administration as it is most convenient, cheap and usually a safe method of drug administration. For many advantages, orally taken medications are much preferred than those of other routes. The choice of appropriate route in a given situation depends both on drug as well as patient related factors. There are various routes of administration, each of which has associated advantages and disadvantages. What are the advantages and disadvantages of oral route. As known worldwide, taking a medicine via oral route is one of the best options. Topically and transdermally administered opioids are characterised by a lower risk of addiction compared to oral and parenteral routes. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Theyll give your presentations a professional, memorable appearance the kind of sophisticated look that todays audiences expect. Aug 15, 20 there are various routes of administration, each of which has associated advantages and disadvantages. Although soliddose forms such as tablets and capsules have a high degree of drug stability and provide accurate dosage, the oral route is problematic because of the unpredictable nature of gastrointestinal absorption.
In this method of administration, drug is applied on to skin or other body surfaces. A free powerpoint ppt presentation displayed as a flash slide show on id. What are the advantages and disadvantages of parenteral. Low risk of systemic adverse events and drug interactions. It means giving the drug by mouth by digestive system. Mar 17, 2018 the transdermal route apart from the abovementioned advantages and provision of long period of analgesia may be more convenient, especially for patients who are unable to take drugs orally.
Pdf systemic absorption of a drug depends on its physicochemical properties, the nature of. This is due to its simplicity, convenience and safety provided. This route of administration is possible if the drug is in liquid dosage form. Drug delivery is targeted to the respiratory system for local pulmonary effect medicine goes to the target directly. Each route has specific purposes, advantages, and disadvantages. Transdermal and topical drug administration in the. Start studying advantages and disadvantages of different routes of administration. Worlds best powerpoint templates crystalgraphics offers more powerpoint templates than anyone else in the world, with over 4 million to choose from. Absorption after oral administration can be quite variable.
Practitioners recognize the rapid onset, relative reliability, and the general lack of patient discomfort when drugs are administered by the transmucosal and transdermal routes. Oral route is the most common route of drug administration. In this administration the drug is administered in the gaseous form. Routes of administration and dosage forms pharmacology. Disadvantages are poor absorption in peripheral circulatory. Injectable preparations are usually sterile solutions or suspensions of drug in water. There are various routes of administration available, each of which has associated advantages and disadvantages. Advantages and disadvantages of thetopical route local therapeutic. Most of the drugs can be administered by different routes.
You will get here advantages and disadvantages of routes of drug administration. Disadvantages are that the route is not acceptable for selfadministration, it may be painful, and if any adverse effects occur to a depot formulation, it cannot be removed. All the routes of drug administration need to be understood in terms of their implications for the effectiveness of the drug therapy and the patients experience of drug treatment. Enteral administration involves absorption of the drug via the gi tract and includes oral, gastric or duodenal e. Routes of administration an overview sciencedirect topics. The iv route is the fastest method for delivering systemic drugs. Routes can also be classified based on where the target of action is. This route is where a medicament is applied on to skin to produce its effects. Parenteral route of administration and dosage forms a drug given parenterally is one given by a route other than the mouth topical dosage forms are considered separately. Oral route oral refers to two methods of administration.
Oral route advantages safer cheaper painless convenient for repeated and prolonged use. Adjusted odds ratio or 95% confidence interval of nauseavomiting in iv and sc group relative to the oral group was 4. Oral administration of nanosuspension dds is propitious to improve the bioavailability of poorly soluble drugs. It can provide fluids, electrolytes, and nutrition. Learn drug routes administration advantages disadvantages with free interactive flashcards. Parenteral drug administration their types, advantages and.
Each route has several variations, and each offers distinct advantages and disadvantages. Monica may lopez september 06, 2016 common routes of drug administration route bioavailability advantages disadvantages drugs. Oral administration will be covered in more detail in subsequent chapters. Different routes are oral route, sublingual route, rectal route, parentral routes, subcutaneous, intravenous, intramuscular. This article throws light upon the three main routes of drug administration. Drug administration by inhalation inhalers drugs are introduced into the body by several routes. Systemic side effects are fewer and less severe than with oral parenteral therapy most medicine stays in the target. Advantages and disadvantages of routes of drug administration. Jan 01, 2014 advantages and disadvantages of the parenteral route. Oral administration is a route of administration where a substance is taken through the mouth.
Most drugs can be administered by a variety of routes. It has several advantages over its parenteral counterparts box 4. They have administered sedatives, narcotics, and a variety of other medications by transdermal, sublingual, nasal, rectal, and even tracheal. Advantages and disadvantages of the topical route disadvantages of the topical route rectal administration is a preferred method when. About sublingual and buccal medication administration. Intravenous route advantages iv is the most common parenteral route. Click again to see term tap again to see term you just studied 25 terms. Some advantages of administering drugs through the oral mucosa are. The iv route was linked with higher rates of all adverse events, the sc route with moderate rates, and the oral route with fewer overall rates. Jan 21, 2019 you will get here advantages and disadvantages of routes of drug administration. Adjusted odds ratio or 95% confidence interval of nauseavomiting in iv and sc group relative to the oral group.
Use of inhaled epinephrine for relief of asthma was reported as early as 1929, in england. Administering a drug through the iv route involves the introduction of a drug solution through a needle, directly into a vein. Transdermal and topical drug administration in the treatment. Some drugs like oxymorphone have a really low boa when taken orally, only 30%40% is able to. The optimal choice of medication administration route. Oral dosage forms advantages, disadvantages, and classification. The key features of various routes are discussed here see table 21. Advantages and disadvantages of different routes of. Drug administration drugs msd manual consumer version. American academy of pediatrics alternative routes of. Common examples include oral and intravenous administration. It may be in the form of tablets, capsules, syrup, emulsions or powders.